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TECHNICAL PAPERS

Flow Structure and Particle Transport in a Triple Bifurcation Airway Model

[+] Author and Article Information
Z. Zhang

Center for Environmental Medicine and Lung Biology, The University of North Carolina, Chapel Hill, NC 27599

C. Kleinstreuer

Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC 27695-7910

C. S. Kim

Human Studies Division, National Health and Environmental Effects Research Laboratory, U.S. EPA, Research Triangle Park, NC 27711

J. Fluids Eng 123(2), 320-330 (Dec 27, 2000) (11 pages) doi:10.1115/1.1359525 History: Received January 09, 2000; Revised December 27, 2000
Copyright © 2001 by ASME
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References

Weibel, E. R., 1963, Morphometry of the Human Lung, Academic Press, New York.
Horsfield,  K., and Cumming,  G., 1968, “Morphology of the Bronchial Tree in man,” J. Appl. Physiol., 24, pp. 373–383.
Kim,  C. S., Lee,  B. K., Lewars,  G. G., and Sackner,  M. A., 1983, “Deposition of Aerosol Particles and Flow Resistance in Mathematical and Experimental Airway Models,” J. Appl. Physiol., 55, pp. 154–163.
Balásházy,  I., 1994, “Simulation of Particle Trajectories in Bifurcating Tubes,” J. Comput. Phys., 110, pp. 11–22.
Gatlin, B., Cuicchi, C., Hammersley, J., Olson, D., Reddy, R., and Burnside, G., 1997, “Particle Path and Wall Deposition Patterns in Laminar Flow Through a Bifurcation,” ASME Vol. FEDSM97, Vancouver, British Columbia, Canada, pp. 1–6.
Farag, A., Hammersley, J., Olson, D., and Ng, T., 1998, “Fluid Mechanics of a Symmetric Bifurcation Model of the Human Pulmonary System,” ASME Vol. FEDSM98, Washington, DC, pp. 1–8.
Farag, A., Ng, T., Hammersley, J., and Olson, J., 1998, “Fluid Mechanics of An Asymmetric Bifurcation Model of Human Pulmonary System,” ASME Vol. FEDSM98, Washington, DC, pp. 1–8.
Wilquem,  F., and Degrez,  G., 1997, “Numerical Modeling of Steady Inspiratory Airflow Through a Three-Generation Model of the Human Central Airways,” ASME J. Biomech. Eng., 119, pp. 59–65.
Lee,  J. W., Goo,  J. H., and Chung,  M. K., 1996, “Characteristics of Inertial Deposition in a Double Bifurcation,” J. Aerosol Sci., 27, pp. 119–138.
Comer,  J. K., Kleinstreuer,  C., Hyun,  S., and Kim,  C. S., 2000, “Aerosol Transport and Deposition in Sequentially Bifurcating Airways,” ASME J. Biomech. Eng., 122, pp. 152–158.
Kleinstreuer, C., Comer, J. K., Zhang, Z., and Kim, C. S., 1999, “Computer Simulation of Aerosol Transport and Deposition in Multi-generation Airway Models,” First Joint Meeting of BMES & EMBS, Atlanta, GA, October 13–16; Conference Proceedings, Fouke, J. M., Nerem, R. M., eds.
Kim,  C. S., and Iglesias,  A. J., 1989, “Deposition of Inhaled Particles in Bifurcating Airway Models: I. Inspiratory Deposition,” Journal of Aerosol Medicine, 2, pp. 1–14.
Kim,  C. S., and Fisher,  D. M., 1999, “Deposition Characteristics of Aerosol Particles in Successively Bifurcating Airway Models,” Aerosol. Sci. Technol., 31, pp. 198–220.
Zhang, Z., Kleinstreuer, C., and Kim, C. S., 2001, “Computational Analysis of Micron-Particle Deposition in a Human Triple Bifurcation Airway Model,” Computer Methods in Biomechanics and Biomedical Engineering (in press).
Horsfield,  K., Dart,  G., Olson,  D. E., Filley,  G. F., and Cumming,  G., 1971, “Models of the Human Bronchial Tree,” J. Appl. Physiol., 31, pp. 207–217.
Philips,  C. G., and Kaye,  S. R., 1997, “On the Asymmetry of Bifurcation in the Bronchial Tree,” Respir. Physiol., 107, pp. 85–98.
Chang,  H. K., and El Masry,  O. A., 1982, “A Model Study of Flow Dynamics in Human Central Airways. Part I: Axial Velocity Profiles,” Respir. Physiol., 49, pp. 75–95.
Isabey,  D., and Chang,  H. K., 1982, “A Model Study of Flow Dynamics in Human Central Airways. Part II: Secondary Flow Velocities,” Respir. Physiol., 49, pp. 97–113.
Chang, H. K., and Menon, A. S., 1985, “Air Flow Dynamics in the Human Airways,” Aerosols in Medicine. Principles, Diagnosis and Therapy, F. Moren, M. T. Newhouse, and M. B. Dolovich, eds., Elsevier Science, Amsterdam, pp. 77–122.
Oho, K., and Amemiya, R., 1980, Practical Fiberoptic Bronchoscopy, Igaku-Shoin, Tokyo.
Pedley, T. J., Schroter, R. C., and Sudlow, M. F., 1977, “Gas Flow and Mixing in The Airways,” Bioengineering Aspects of the Lung, West, J. B., ed., Marcel Dekker, New York.
Martonen,  T. B., Yang,  Y., and Xue,  Z. Q., 1994, “Influences of Cartilaginous Rings on Tracheobronchial Fluid Dynamics,” Inhalation Toxicol., 6, pp. 185–203.
Comer, J. K., 1998, “Computational Two-Phase Flow Analyses and Applications to Gas-Liquid and Gas-Solid Flows,” PhD thesis, Mechanical and Aerospace Engineering Department, North Carolina State University, Raleigh, NC.
Kleinstreuer, C., 1997, Engineering Fluid Dynamics—An Interdisciplinary Systems Approach, Cambridge University Press, NY.
Clift, R., Grace, J. R., and Weber, M. E., 1978, Bubbles Drops and Particles, Academic Press, NY.
Zhang, Z., and Kleinstreuer, C., 2001, “Effect of Particle Inlet Distribution on Deposition in A Triple Bifurcation Lung Airway Model,” Journal of Aerosol Medicine, 14 , pp. 13–29.
Zhang,  Z., Kleinstreuer,  C., and Kim,  C. S., 2000, “Effects of Asymmetric Branch Flow Rates on Aerosol Deposition in Bifurcating Airways,” J. Med. Eng. Technol. 24, pp. 192–202.
AEA Technology, 1997, CFX-4.2: Solver, CFX International, Oxfordshire, UK.
Patankar, S. V., 1983, Numerical Heat Transfer and Fluid Flow, Hemisphere, NY.
Lonsdale,  R. D., 1993, “An algebraic multi-grid solver for the Navier Stokes equations on unstructured meshes,” Int. J. Numer. Methods Heat Fluid Flow, 3, pp. 3–14.
Gear, C. W., 1971, Numerical Initial Value Problems in Ordinary Differential Equations, Prentice-Hall, Englewood Cliffs, NJ.
Johnston, J. R., Isles, K. D., and Muir, D. C. F., 1977, “Inertial Deposition of Particles in Human Branching Airways,” Inhaled Particles IV, Walton, W. H., ed., Pergamon Press, Oxford, pp. 61–72.
Comer, J. K., Kleinstreuer, C., Longest, P. W., Kim, C. S., and Kinsey, J. S., 1998, “Computational Aerosol Transport and Deposition Analyses for Human Exposure Chambers and Model Respiratory Airways,” ASME Vol. FEDSM98, Washington, DC, pp. 1–6.
Kim,  C. S., Fisher,  D. M., Lutz,  D. J., and Gerrity,  T. R., 1994, “Particle Deposition in Bifurcating Airway Models with Varying Airway Geometry,” J. Aerosol Sci., 25, pp. 567–581.
Comer, J. K., Kleinstreuer, C., and Zhang, Z., 2001, “Flow Structures and Particle Deposition Patterns in Double Bifurcation Airway Models. Part 1. Air Flow Fields,” J. Fluid Mech., in press.
Eaton,  J. K., and Fessler,  J. R., 1994, “Preferential Concentration of Particles by Turbulence,” Int. J. Multiphase Flow, 20, Suppl., pp. 169–209.

Figures

Grahic Jump Location
Schematic of symmetric in-plane triple bifurcation geometry: (a) block structure and (b) finite volume mesh
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Comparison between computed data set and measured η(St) correlation for: (a) first bifurcation and (b) second bifurcation of a symmetric planar bifurcation
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Coordinate systems and locations of various cross sections used for visualization of air flow and particle transport in a triple bifurcation model
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Mid-plane axial flow patterns of the triple bifurcation model: (a) Re=500 and (b) Re=2000
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Axial velocity contours and secondary velocity plots at different cross sections in the triple bifurcation model for Re=500
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Axial velocity contours and secondary velocity plots at different cross sections in the triple bifurcation model for Re=2000
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Particle distributions and flow directions in the triple bifurcation at different cross sections: (a) Re=500,St=0.04 and (b) Re=2000,St=0.04. (Note: • indicates impacting particles and the arrow only indicates the direction of particle motion.)
Grahic Jump Location
Particle distributions and flow directions in the triple bifurcation at different cross sections: (a) Re=500,St=0.12 and (b) Re=2000,St=0.12. (Note: • indicates impacting particles and the arrow only indicates the direction of particle motion.)
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Time evolution for a volumetric particle pulse in the triple bifurcation for St=0.12 and Re=2000

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