Quantitative Evaluation of Blood Damage in a Centrifugal VAD by Computational Fluid Dynamics

[+] Author and Article Information
Xinwei Song, Houston G. Wood

Mechanical and Aerospace Engineering Department, Virginia Artificial Heart Institute, University of Virginia, Charlottesville, VA USA

Amy L. Throckmorton

Biomedical Engineering Department, Virginia Artificial Heart Institute, University of Virginia, Charlottesville, VA USA

James F. Antaki

McGowan Center for Artificial Organ Development, University of Pittsburgh, Pittsburgh, PA USA

Don B. Olsen

Utah Artificial Heart Institute, Salt Lake City, UT USA

J. Fluids Eng 126(3), 410-418 (Jul 12, 2004) (9 pages) doi:10.1115/1.1758259 History: Received April 01, 2003; Revised November 17, 2003; Online July 12, 2004
Copyright © 2004 by ASME
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Grahic Jump Location
Shear Stress Power Versus Time for Particle #1
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Shear stress power versus time for particle #2
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Shear stress power versus time for particle #3
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Shear stress power versus time for particle #9
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Shear stress power versus time for particle #10
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Shear rate (dτ/dt) over time for particle #2
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Shear rate (dτ/dt) over time for particle #3
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Centrifugal Blood Pump Prototype-CF4b: This VAD includes an inlet elbow, spindle, impeller, clearance region between the rotor and housing, exit volute and diffuser.
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Isotimic Plot of Shear Stress along Blade-tip Surface: This surface along the tip of the blade shows the highest levels of shear stresses in the pump. Higher shear stresses exist along the trailing edge of the impeller region prior to the entering the exit volute and directly along the blades, particularly at the trailing edge. Maximum shear stress values of 250 Pa are found in this plane.
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Streaklines Colored by Exposure Time: Particles released at the inlet port of the computational model and travel through the pump for a given residence time.
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Streaklines for 388 Particles, Colored by Shear Stress: Particles released at inlet port and travel along streaklines or pathlines during steady state flow conditions. Shear stress values are plotted for each nodal location along the streakline for each particle.
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Distribution of Blood Damage Index for Population of 388 Pathlines Studied: Maximum blood damage indices averaged 2% for only a few particles. Most particles experienced a damage index less than 0.5%.
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Distribution of Exposure Time for Population of Particles Studied: Approximately 322 of the 388 particles in this study took less than 0.19 s to travel through the computational flow model. Average residence times are 0.34 second with a maximum exposure time of 5.3 s due to a possible vortex region.



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