An experimental study is performed to analyze the shear driven droplet shedding on cold substrates with different airflow speeds typical of those in the flight conditions. Understanding the mechanism of simultaneous droplet shedding, coalescence, and solidification is crucial to devise solutions for mitigating aircraft in-flight icing. To mimic this scenario, the experimental setup is designed to generate shear flow as high as 90 m/s. The droplet shedding at high-speed is investigated on a cold surface (0 and −5 °C) of different wettabilities ranging from hydrophilic to superhydrophobic. Result analyses indicate that on a hydrophilic substrate, the droplets form a rivulet, which then freezes on the cold plate. In contrast, on the superhydrophobic surface, there is no rivulet formation. Instead, droplets roll over the substrate and detach from it under the effect of high shear flow.