In this paper, a numerical model was developed to describe the wire-plate electrostatic precipitator, commonly called electronic air cleaners. Electrostatic precipitator have been widely used to control particulate pollutants, which adversely affect human health. In this model, the complex interactions between fluid dynamics, electric fields and particle dynamics are considered. Therefore different approach methods are used in this study for each field, Eulerian reference frame was used for the fluid flow field and the electric field, Lagrangian reference frame used for the particles trajectories. In order to describe corona phenomena around high voltage electrode, electric field and ion current density field in electrostatic precipitator are numerically calculated using the iterative method for corona discharge model suggested by Kim (2010). The most important concept in electrostatic precipitator is the electric force applied to particles through the particle charging phenomena. The charge acquired by the particle in the corona region was obtained by combining the field charge, the diffusion charge and the time available for charging being the residence time of the particle in the corona region. In order to simulate more accurately, the charging model suggested by Lawless (1996) is used for the charging phenomena of particles by corona discharge because this model was designed to predict combination effect of diffusion charge and field charge. The diminution of particle concentration along the collection plate was derived from Deutsch’s theory, and migration velocity of the particle was developed from the condition that the magnitude of Coulomb force is equal to that of Stoke’s resistance force. This model is implemented by UDF in commercial software Fluent and validated with experimental and numerical results from literatures. CFD results had been compared with various experimental data obtained by Penney&Matick, Parasram and Kihm. Our results shows good agreement in terms of distributions of electric potential, current density, electrohydrodynamic flow pattern, and particle trajectories as well as corona current and collection efficiency. From this simulation, the effect of wire arrangement on electrostatic precipitator characteristics and particle charging are investigated. Both inline and staggered arrangements of wire electrode have been considered for fixed values of gas velocity equal to 2m/s. Applied voltage on wire electrode varies 6∼13kV and particle diameter is 4μm. For low voltage condition, staggered arrangement of wire electrode caused the turbulent effect so that collection efficiency increase more than inline arrangement. However, collection efficiency decrease in high voltage condition because electric force applied on particles passing between the wire electrodes is canceled out by both side wire electrodes.