In Vivo Determination of Elastic Modulus of Canine Cardiac Muscle

[+] Author and Article Information
J. F. Lafferty, E. P. McCutcheon, J. E. Funk, A. M. Higgins

Wenner-Gren Research Laboratory, University of Kentucky, Lexington, Ky.

J. Basic Eng 94(4), 912-916 (Dec 01, 1972) (5 pages) doi:10.1115/1.3425589 History: Received July 28, 1972; Online October 27, 2010


A practical technique was developed for in vivo determinations of the mechanical properties of canine left ventricle. A “quick stretch” was accomplished by rapid injection of isotonic saline into the ventricle during isovolumetric systole. The experimental pressure-volume data and a stress-strain analysis of the left ventricle as a thick-walled sphere permitted determination of the effective elastic modulus as a function of the mean circumferential stress. The elastic modulus E was found to be a linear function of the mean tangential stress σ throughout the isovolumetric systolic period; the slope (K, modulus of stiffness) of the Eversus σ curve was 18.8 with a standard deviation of 0.9.

Copyright © 1972 by ASME
Your Session has timed out. Please sign back in to continue.





Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related Journal Articles
Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In