A computational fluid dynamics (CFD) model of the cerebrospinal fluid system was constructed based on a simplified geometry of the brain ventricles and their connecting pathways. The flow is driven by a prescribed sinusoidal motion of the third ventricle lateral walls, with all other boundaries being rigid. The pressure propagation between the third and lateral ventricles was examined and compared to data obtained from a similar geometry with a stenosed aqueduct. It could be shown that the pressure amplitude in the lateral ventricles increases in the presence of aqueduct stenosis. No difference in phase shift between the motion of the third ventricle walls and the pressure in the lateral ventricles because of the aqueduct stenosis could be observed. It is deduced that CFD can be used to analyze the pressure propagation and its phase shift relative to the ventricle wall motion. It is further deduced that only models that take into account the coupling between ventricles, which feature a representation of the original geometry that is as accurate as possible and which represent the ventricle boundary motion realistically, should be used to make quantitative statements on flow and pressure in the ventricular space.
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e-mail: Yiannis.Ventikos@eng.ox.ac.uk
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April 2005
Article
Computational Modeling of the Mechanical Behavior of the Cerebrospinal Fluid System
Vartan Kurtcuoglu,
Vartan Kurtcuoglu
Laboratory of Thermodynamics in Emerging Technologies
, Institute of Energy Technology, Swiss Federal Institute of Technology, ETH Zentrum, CH-8092 Zurich, Switzerland
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Dimos Poulikakos,
Dimos Poulikakos
Laboratory of Thermodynamics in Emerging Technologies
, Institute of Energy Technology, Swiss Federal Institute of Technology, ETH Zentrum, CH-8092 Zurich, Switzerland
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Yiannis Ventikos
e-mail: Yiannis.Ventikos@eng.ox.ac.uk
Yiannis Ventikos
Laboratory of Thermodynamics in Emerging Technologies
, Institute of Energy Technology, Swiss Federal Institute of Technology, ETH Zentrum, CH-8092 Zurich, Switzerland
Search for other works by this author on:
Vartan Kurtcuoglu
Laboratory of Thermodynamics in Emerging Technologies
, Institute of Energy Technology, Swiss Federal Institute of Technology, ETH Zentrum, CH-8092 Zurich, Switzerland
Dimos Poulikakos
Laboratory of Thermodynamics in Emerging Technologies
, Institute of Energy Technology, Swiss Federal Institute of Technology, ETH Zentrum, CH-8092 Zurich, Switzerland
Yiannis Ventikos
Laboratory of Thermodynamics in Emerging Technologies
, Institute of Energy Technology, Swiss Federal Institute of Technology, ETH Zentrum, CH-8092 Zurich, Switzerlande-mail: Yiannis.Ventikos@eng.ox.ac.uk
J Biomech Eng. Apr 2005, 127(2): 264-269 (6 pages)
Published Online: November 6, 2004
Article history
Received:
November 17, 2003
Revised:
November 6, 2004
Citation
Kurtcuoglu, V., Poulikakos, D., and Ventikos, Y. (November 6, 2004). "Computational Modeling of the Mechanical Behavior of the Cerebrospinal Fluid System." ASME. J Biomech Eng. April 2005; 127(2): 264–269. https://doi.org/10.1115/1.1865191
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