.... numerical model fluid-structure interaction heart valve asymmetry The aortic valve cusps, or leaflets, are composed of three layers of tissue: the fibrosa on the aortic side, the ventricularis on the left ventricle side, and the spongiosa that lie between them. Most of the collagen fibers...

... of this study was to design an ex vivo tissue culture system to characterize the biological response of heart valve leaflets subjected to a well-defined steady or time-varying shear stress environment. The novel apparatus was designed based on a cone-and-plate viscometer. The device characteristics were defined...

... Phenotype and Extracellular Matrix in Tissue-Engineered Heart Valves During In-Vitro Maturation and In-Vivo Remodeling ,” J. Heart Valve Dis. 0966-8519 , 11 ( 3 ), pp. 308 – 314 ; discussion 314. Hutmacher , D. W. , 2001 , “ Scaffold Design and Fabrication Technologies for Engineering...

...Hsin-Yi Lin; Brian A. Bianccucci; Steven Deutsch; Arnold A. Fontaine; J. M. Tarbell Clinical studies using transcranial Doppler ultrasonography in patients with mechanical heart valves (MHV) have detected gaseous emboli. The relationship of gaseous emboli release and cavitation on MHV has been...