This article illustrates the development and preliminary results of SELINE, a self-opening neural interface. The advantages of this innovative neural interface are: higher selectivity due to its three-dimensional structure and efficient anchorage system to the nervous tissue. The device is made of polyimide that is a lightweight, flexible and biocompatible polymer. The electrode has been microfabricated using lithographic techniques; electrical and mechanical tests have been performed to evaluate the integrity of the device. Successful results have been obtained in the development of the electrode with excellent mechanical and electrical properties.

References

1.
Boretius
,
T.
, et al.,
2010
. “
A Transverse Intrafascicular Multichannel Electrode (time) to Interface With the Peripheral Nerve
”.
J Biosens Bioelectron
,
26
, pp.
62
69
.10.1016/j.bios.2010.05.010
2.
Yoshida
,
K.
, et al.,
2000
. “
Development of the Thin-Film Longitudinal Intrafascicular Electrode
”, Proc 5th Annu Conf IFESS p.
279
.
3.
Goodall
,
E.
, et al.,
1999
. “
Information Contained in Sensory Nerve Recordings Made With Intrafascicular Electrodes
,”
IEEE Trans Biomed Eng.
,
38
, pp.
846
850
.10.1109/10.83604
4.
Ghionzoli
,
A.
, et al.,
2011
. “
Preliminary Results on the Design of a Tool for Inserting Transverse Intrafascicular Multichannel Electrodes
,”
Medicine and Biology Society, Embc
, pp.
7634
7638
.
5.
Lago
,
N.
, et al.,
2007
. “
Assessment of Biocompatibility of Chronically Implanted Polyimide and Platinum Intrafascicular Electrodes
,”
IEEE Trans Biomed Eng.
,
54
, pp.
281
290
.10.1109/TBME.2006.886617
6.
Citi
,
L.
, et al.,
2008
. “
On the Use of Wavelet Denoising and Spike Sorting Techniques to Process Electroneurographic Signals Recorded Using Intraneural Electrodes
”,
J. Neurosci. Meth.
,
172
, pp.
294
302
.10.1016/j.jneumeth.2008.04.025
7.
Cutrone
,
A.
, et al.,
2011
. “
Modelization of a Self-Opening Neural Interface
,”
Med. Eng. Phys.
,
33
, pp.
1254
1261
.10.1016/j.medengphy.2011.06.001
8.
Seymour
,
J.
, et al.,
2007
. “
Neural Probe Design for Reduced Tissue Encapsulation in cns
”.
Biomaterials
,
28
, pp.
3594
3607
.10.1016/j.biomaterials.2007.03.024
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