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Proceedings Papers

Modeling the Thermal Histories of Collagenous Tissues Subjected to Different Heating Modalities

Alptekin Aksan, David S. Nielubowicz, Jr., John J. McGrath
Proc. ASME. IMECE2001, Advances in Heat and Mass Transfer in Biotechnology, 115-124, November 11–16, 2001
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2001/HTD-24433
https://doi.org/10.1115/IMECE2001/HTD-24433
View Paper titled, Modeling the Thermal Histories of Collagenous Tissues Subjected to Different Heating Modalities
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Topics: Biological tissues, Heating, Modeling, Heat, Lasers, Patient treatment, Probes, Shrinkage (Materials), Biomedicine, Disks
Proceedings Papers

Effect of Kinetic and Thermodynamic Transitions of Confined Water on Biomolecules

Eduardo Reátegui, Alptekin Aksan
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 155-156, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192376
https://doi.org/10.1115/SBC2008-192376
View Paper titled, Effect of Kinetic and Thermodynamic Transitions of Confined Water on Biomolecules
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Topics: Water, Microorganisms, Nanopores, Fourier transform infrared spectroscopy, Proteins, Bacteria, Enzymes, Mechanical admittance, Phase transitions, Stability
Proceedings Papers

Desiccation of Geobacter Sulfurreducens: Membrane Response to Osmotic Stress

Vishard Ragoonanan, Jason Malsam, Daniel R. Bond, Alptekin Aksan
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 299-300, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192461
https://doi.org/10.1115/SBC2008-192461
View Paper titled, Desiccation of Geobacter Sulfurreducens: Membrane Response to Osmotic Stress
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Topics: Membranes, Stress, Bacteria, Thin films, Coatings, Electron transport, Latex, Preservation, Sensors
Proceedings Papers

Factors Affecting Protein Distribution and Structure in a Dried Droplet

Vishard Ragoonanan, Alptekin Aksan
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 903-904, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192888
https://doi.org/10.1115/SBC2008-192888
View Paper titled, Factors Affecting Protein Distribution and Structure in a Dried Droplet
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Topics: Drops, Proteins, Drying, Flow (Dynamics), Biomacromolecules, Biomaterials, Preservation, Stability, Storage, Thin films
Proceedings Papers

Use of Raman Microspectroscopy to Study Partioning of Molecules During Freeze-Processing of Protein Solutions

Jinping Dong, Allison Hubel, John C. Bischof, Alptekin Aksan
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 905-906, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193052
https://doi.org/10.1115/SBC2008-193052
View Paper titled, Use of Raman Microspectroscopy to Study Partioning of Molecules During Freeze-Processing of Protein Solutions
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Topics: Cooling, Cryonics, Crystallization, Freezing, Ice, Latent heat, Microspectroscopy, Phase separation, Proteins, Temperature gradient
Proceedings Papers

Quantification of Heterogeneity in Desiccating Droplets

Vishard Ragoonanan, Alptekin Aksan
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 67-68, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176250
https://doi.org/10.1115/SBC2007-176250
View Paper titled, Quantification of Heterogeneity in Desiccating Droplets
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Topics: Drops, Preservation, Drying
Proceedings Papers

Desiccation Response of Geobacter sulfurreducens

Jason A. Malsam, Vishard Ragoonanan, Daniel R. Bond, Alptekin Aksan
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 69-70, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176271
https://doi.org/10.1115/SBC2007-176271
View Paper titled, Desiccation Response of Geobacter sulfurreducens
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Topics: Bacteria, Drying, Fuel cells, Preservation, Sensors, Temperature, Thin films, Water
Proceedings Papers

Thermal Damage Distribution in Human Cornea Following Thermal Keratoplasty: An FTIR Study

Li Zhang, Willem F. Wolkers, Alptekin Aksan
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 79-80, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176239
https://doi.org/10.1115/SBC2007-176239
View Paper titled, Thermal Damage Distribution in Human Cornea Following Thermal Keratoplasty: An FTIR Study
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Topics: Cornea, Damage, Fourier transform infrared spectroscopy, Fibers, Heat, Shrinkage (Materials), Biological tissues, Diseases, Heat treating (Metalworking), Heating
Proceedings Papers

A Structural, Kinetic Model of Soft Tissue Thermomechanics

Triantafyllos Stylianopoulos, Alptekin Aksan, Victor H. Barocas
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 331-332, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176008
https://doi.org/10.1115/SBC2007-176008
View Paper titled, A Structural, Kinetic Model of Soft Tissue Thermomechanics
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Topics: Soft tissues, Thermomechanics, Heat, Patient treatment, Biological tissues, Heating, Modeling, Skin, Temperature, Tendons
Proceedings Papers

Reactive Biomaterial for the Treatment of Herbicide Contaminated Drinking Water: Atrazine Dechlorination

Eduardo Reátegui, Erik Reynolds, Lisa Kasinkas, Amit Aggarwal, Michael J. Sadowsky, Alptekin Aksan, Lawrence P. Wackett
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 347-348, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80205
https://doi.org/10.1115/SBC2012-80205
View Paper titled, Reactive Biomaterial for the Treatment of Herbicide Contaminated Drinking Water: Atrazine Dechlorination
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Topics: Biomaterials, Water, Activated carbon, Environmental Protection Agency, Water treatment
Proceedings Papers

Encapsulation of Mammalian Cells in Nanoporous Silica Gels: Interactions at the Biointerface

Eduardo Reátegui, Lisa Kasinkas, Alptekin Aksan
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 667-668, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80211
https://doi.org/10.1115/SBC2012-80211
View Paper titled, Encapsulation of Mammalian Cells in Nanoporous Silica Gels: Interactions at the Biointerface
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Topics: Biosensors, Biotechnology, Energy conversion, Mechanical properties, Patient treatment, Thermal stability
Journal Articles

Acute Recovery of Patellar Tendon From Heat-Induced Shrinkage and Its Inhibition by Cross-Linking

Alptekin Aksan, John J. McGrath
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. September 2010, 132(9): 091007.
https://doi.org/10.1115/1.4001924
Published Online: August 19, 2010
View Article titled, Acute Recovery of Patellar Tendon From Heat-Induced Shrinkage and Its Inhibition by Cross-Linking
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Topics: Biological tissues, Heat, Heating, Shrinkage (Materials), Temperature, Tendons, Mechanical properties, Patient treatment, Thermomechanics
Journal Articles

Frontiers in Biotransport: Water Transport and Hydration

Alptekin Aksan, Allison Hubel, John C. Bischof
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technology Review
J Biomech Eng. July 2009, 131(7): 074004.
https://doi.org/10.1115/1.3173281
Published Online: July 28, 2009
View Article titled, Frontiers in Biotransport: Water Transport and Hydration
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Topics: Biological tissues, Water, Biotransport
Journal Articles

Biotransport Special Issue

Alptekin Aksan, Ph.D., Allison Hubel, Ph.D., John Bischof, Ph.D.
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Guest Editorial
J Biomech Eng. July 2009, 131(7): 070301.
https://doi.org/10.1115/1.3185352
Published Online: July 28, 2009
View Article titled, Biotransport Special Issue
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Topics: Biotransport, Cancer, Patient treatment, Proteins, Biomembranes, Molecular biophysics, Nanotechnology, Tumors
Journal Articles

Structural Changes in Confined Lysozyme

Eduardo Reátegui, Alptekin Aksan
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. July 2009, 131(7): 074520.
https://doi.org/10.1115/1.3171565
Published Online: July 27, 2009
View Article titled, Structural Changes in Confined Lysozyme
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Topics: Enzymes, Fluorescence, Fourier transform infrared spectroscopy, High temperature, Proteins, Temperature, Water, Dynamics (Mechanics), Low temperature, Macromolecules
Proceedings Papers

Ratiometric Laser-Induced Fluorescence (LIF) Thermography of Radiofrequency Heated Tissue Phantoms

Damien J. Fron, Alptekin Aksan, John J. McGrath
Proc. ASME. IMECE2002, Advances in Bioengineering, 1-8, November 17–22, 2002
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2002-32353
https://doi.org/10.1115/IMECE2002-32353
View Paper titled, Ratiometric Laser-Induced Fluorescence (LIF) Thermography of Radiofrequency Heated Tissue Phantoms
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Topics: Biological tissues, Fluorescence, Lasers, Phantoms, Thermography, Heating, Probes, Temperature, Temperature measurement, Physiology
Proceedings Papers

Heat-Induced Denaturation of Collagenous Tissue: A Comparison of Numerical Simulations With OCT and MRI Data

Alptekin Aksan, Arthur F. Gmitro, Jennifer K. Barton, Scott Anseth, Steven P. Arnoczky, Damien J. Fron, John J. McGrath
Proc. ASME. IMECE2002, Advances in Heat and Mass Transfer in Biotechnology, 51-54, November 17–22, 2002
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2002-33690
https://doi.org/10.1115/IMECE2002-33690
View Paper titled, Heat-Induced Denaturation of Collagenous Tissue: A Comparison of Numerical Simulations With OCT and MRI Data
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Topics: Biological tissues, Computer simulation, Heat, Magnetic resonance imaging, Biomedicine, Coherence (Optics), Heating, Mechanical properties, Shrinkage (Materials), Skin
Proceedings Papers

Glass Formation During Room Temperature, Isothermal Drying

Alptekin Aksan, Mehmet Toner
Proc. ASME. IMECE2003, Advances in Bioengineering, 7-8, November 15–21, 2003
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2003-43049
https://doi.org/10.1115/IMECE2003-43049
View Paper titled, Glass Formation During Room Temperature, Isothermal Drying
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Topics: Drying, Glass, Temperature, Glass transition, Differential scanning calorimetry, Molecular weight, Stability, Vitrification
Proceedings Papers

Measurement of Molecular Mobility in Mammalian Cells

Alptekin Aksan, Mehmet Toner
Proc. ASME. IMECE2004, Advances in Bioengineering, 91-92, November 13–19, 2004
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2004-61508
https://doi.org/10.1115/IMECE2004-61508
View Paper titled, Measurement of Molecular Mobility in Mammalian Cells
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Topics: Mechanical admittance, Water, Preservation, Chemical reactions, Cryonics, Freezing, Glass, Rotors
Journal Articles

Thermal Damage Prediction for Collagenous Tissues Part I: A Clinically Relevant Numerical Simulation Incorporating Heating Rate Dependent Denaturation

Alptekin Aksan, John J. McGrath, David S. Nielubowicz,, Jr.
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. February 2005, 127(1): 85–97.
https://doi.org/10.1115/1.1835355
Published Online: March 8, 2005
View Article titled, Thermal Damage Prediction for Collagenous Tissues Part I: A Clinically Relevant Numerical Simulation Incorporating Heating Rate Dependent Denaturation
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Topics: Biological tissues, Damage, Heating, Lasers, Temperature, Simulation, Heat