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Rafael V. Davalos
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Journal Articles

Experimental and Numerical Investigation of Parameters Affecting High-Frequency Irreversible Electroporation for Prostate Cancer Ablation

Kenneth N. Aycock, Ram Anand Vadlamani, Edward J. Jacobs, IV, Khan Mohammad Imran, Scott S. Verbridge, Irving C. Allen, Navid Manuchehrabadi, Rafael V. Davalos
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2022, 144(6): 061003.
Paper No: BIO-21-1372
https://doi.org/10.1115/1.4053595
Published Online: February 15, 2022
View Article titled, Experimental and Numerical Investigation of Parameters Affecting High-Frequency Irreversible Electroporation for Prostate Cancer Ablation
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Topics: Ablation (Vaporization technology), Biological tissues, Cancer, Damage, Delays, Electric fields, Electroporation, Fire, Tumors, Performance
Includes: Supplementary data
Journal Articles

A Comparative Modeling Study of Thermal Mitigation Strategies in Irreversible Electroporation Treatments

Kenneth N. Aycock, Sabrina N. Campelo, Rafael V. Davalos
Journal: ASME Journal of Heat and Mass Transfer
Publisher: ASME
Article Type: Research-Article
J. Heat Mass Transfer. March 2022, 144(3): 031206.
Paper No: HT-21-1663
https://doi.org/10.1115/1.4053199
Published Online: January 18, 2022
View Article titled, A Comparative Modeling Study of Thermal Mitigation Strategies in Irreversible Electroporation Treatments
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Topics: Biological tissues, Cooling, Damage, Electrodes, Electroporation, Modeling, Phase change materials, Probes, Temperature, Temperature effects
Includes: Supplementary data
Proceedings Papers

An Autonomous Cell Type Selective Irreversible Electroporation Microsystem Using Insulator Based Dielectrophoresis (IDEP)

Hadi Shafiee, Rafael V. Davalos
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 591-592, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193040
https://doi.org/10.1115/SBC2008-193040
View Paper titled, An Autonomous Cell Type Selective Irreversible Electroporation Microsystem Using Insulator Based Dielectrophoresis (IDEP)
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Topics: Dielectrophoresis, Electroporation, Microelectromechanical systems, Cancer, Electric fields, Blood, Cell membranes, Diseases, Electrodes, Electrolytes
Proceedings Papers

Irreversible Electroporation (IRE) to Treat Brain Tumors

Paulo A. Garcia, John Robertson, John Rossmeisl, Rafael V. Davalos
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 101-102, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192992
https://doi.org/10.1115/SBC2008-192992
View Paper titled, Irreversible Electroporation (IRE) to Treat Brain Tumors
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Topics: Brain, Electroporation, Tumors, Cell membranes, Ions, Macromolecules, Permeability, Transients (Dynamics)
Proceedings Papers

Adapting the Cassini Curve to Approximate In Vivo Irreversible Electroporation Ablations in Porcine Liver

Paulo A. Garcia, Christopher B. Arena, Robert E. Neal, II, S. Nahum Goldberg, Eliel Ben-David, Rafael V. Davalos
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT42A005, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14817
https://doi.org/10.1115/SBC2013-14817
View Paper titled, Adapting the Cassini Curve to Approximate In Vivo Irreversible Electroporation Ablations in Porcine Liver
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Topics: Electroporation, Liver, Tumors, Ablation (Vaporization technology), Biological tissues, Electric fields, Electrodes, Membranes, Permeability, Resolution (Optics)
Proceedings Papers

In Vivo Validation of Irreversible Electroporation Electric Field Threshold for Prostate Tissue

Robert E. Neal, II, Helen Kavnoudias, Franklin Rosenfeldt, Ruchong Ou, James Marron, Rafael V. Davalos, Kenneth R. Thomson
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT42A003, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14425
https://doi.org/10.1115/SBC2013-14425
View Paper titled, In Vivo Validation of Irreversible Electroporation Electric Field Threshold for Prostate Tissue
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Topics: Biological tissues, Electric fields, Electroporation, Tumors, Ablation (Vaporization technology), Blood, Computer simulation, Electrodes, Heat sinks, Imaging
Journal Articles

An Experimental and Numerical Investigation of Phase Change Electrodes for Therapeutic Irreversible Electroporation

Christopher B. Arena, Roop L. Mahajan, Marissa Nichole Rylander, Rafael V. Davalos
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2013, 135(11): 111009.
Paper No: BIO-13-1182
https://doi.org/10.1115/1.4025334
Published Online: October 3, 2013
View Article titled, An Experimental and Numerical Investigation of Phase Change Electrodes for Therapeutic Irreversible Electroporation
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Topics: Electrodes, Electroporation, Temperature, Biological tissues, Gallium, Melting point
Proceedings Papers

An Alternative Technique for Dielectrophoretic (DEP) Cell Manipulation: Contact-Less DEP

Hadi Shafiee, Michael B. Sano, John Caldwell, Rafael V. Davalos
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1151-1152, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206809
https://doi.org/10.1115/SBC2009-206809
View Paper titled, An Alternative Technique for Dielectrophoretic (DEP) Cell Manipulation: Contact-Less DEP
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Topics: Bubbles, Dielectrophoresis, Electric fields, Electrical properties, Electrodes, Fluids, Microchannels, Particulate matter, Polarization (Electricity), Polarization (Light)
Proceedings Papers

Pilot Study of Irreversible Electroporation to Treat Brain Cancer

Paulo A. Garcia, Subbiah Elankumaran, Rafael V. Davalos
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 495-496, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206696
https://doi.org/10.1115/SBC2009-206696
View Paper titled, Pilot Study of Irreversible Electroporation to Treat Brain Cancer
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Topics: Brain, Cancer, Electroporation, Biological tissues, Ablation (Vaporization technology), Cell membranes, Blood vessels, Electric fields, Electrodes, Tumors
Proceedings Papers

Dielectrophoretic Microweaving: Biofabrication of Aligned Bacterial Nanocellulose for Regenerative Medicine

Michael B. Sano, Rafael V. Davalos, Paul Gatenholm
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 563-564, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206787
https://doi.org/10.1115/SBC2009-206787
View Paper titled, Dielectrophoretic Microweaving: Biofabrication of Aligned Bacterial Nanocellulose for Regenerative Medicine
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Topics: Biomedicine, Bacteria, Polymers, Biocompatibility, Biological tissues, Manufacturing, Mechanical properties, Nanoscale phenomena
Proceedings Papers

A Comparison Between the Pulsed and Duty Cycle Approaches Used to Capture the Thermal Response of Tissue During Electroporation-Based Therapies

Paulo A. Garcia, John A. Pearce, Rafael V. Davalos
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 945-946, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80574
https://doi.org/10.1115/SBC2012-80574
View Paper titled, A Comparison Between the Pulsed and Duty Cycle Approaches Used to Capture the Thermal Response of Tissue During Electroporation-Based Therapies
Open the PDF for A Comparison Between the Pulsed and Duty Cycle Approaches Used to Capture the Thermal Response of Tissue During Electroporation-Based Therapies in another window
Topics: Biological tissues, Cycles, Electroporation, Patient treatment, Tumors, Ablation (Vaporization technology), Electric fields, Electrodes, Membranes, Permeability
Proceedings Papers

Phase Change Electrodes for Reducing Joule Heating During Irreversible Electroporation

Christopher B. Arena, Roop L. Mahajan, Marissa Nichole Rylander, Rafael V. Davalos
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 473-474, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80825
https://doi.org/10.1115/SBC2012-80825
View Paper titled, Phase Change Electrodes for Reducing Joule Heating During Irreversible Electroporation
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Topics: Electrodes, Electroporation, Heating, Joules, Biological tissues, Ablation (Vaporization technology), Electric fields, Blood vessels, Cell membranes, Magnetic resonance imaging
Proceedings Papers

Investigating Dielectrophoretic Signature of Mouse Ovarian Surface Epithelial Cells, Macrophages and Fibroblasts

Alireza Salmanzadeh, Harsha Kittur, Michael B. Sano, Mark A. Stremler, P. Christopher Roberts, Eva M. Schmelz, Rafael V. Davalos
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 35-36, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80872
https://doi.org/10.1115/SBC2012-80872
View Paper titled, Investigating Dielectrophoretic Signature of Mouse Ovarian Surface Epithelial Cells, Macrophages and Fibroblasts
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Topics: Fibroblasts, Cancer, Fluids, Dielectrophoresis, Electrical properties
Proceedings Papers

Irreversible Electroporation Using the Vasculature of an Organ as Fluid Electrodes

Michael B. Sano, Christopher B. Arena, Paulo A. Garcia, Rafael V. Davalos
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 475-476, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80870
https://doi.org/10.1115/SBC2012-80870
View Paper titled, Irreversible Electroporation Using the Vasculature of an Organ as Fluid Electrodes
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Topics: Electrodes, Electroporation, Fluids, Electric fields, Permeability, Cell membranes, Ducts, Lipid bilayers, Nanoscale phenomena, Resolution (Optics)
Proceedings Papers

Pilot Study on the Enhancement of Irreversible Electroporation (IRE) With Carbon Nanotubes (CNT)

Christopher B. Arena, Marissa Nichole Rylander, Rafael V. Davalos
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 347-348, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-204262
https://doi.org/10.1115/SBC2009-204262
View Paper titled, Pilot Study on the Enhancement of Irreversible Electroporation (IRE) With Carbon Nanotubes (CNT)
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Topics: Carbon nanotubes, Electroporation, Biological tissues, Ablation (Vaporization technology), Cell membranes, Electrodes, Surgery, Tumors
Proceedings Papers

Feasibility Study for Applying Irreversible Electroporation to the Treatment of Breast Cancer

Robert E. Neal, II, Ravi Singh, Suzy Torti, Rafael V. Davalos
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 209-210, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206732
https://doi.org/10.1115/SBC2009-206732
View Paper titled, Feasibility Study for Applying Irreversible Electroporation to the Treatment of Breast Cancer
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Topics: Cancer, Electroporation, Biological tissues, Ablation (Vaporization technology), Cell membranes, Computer simulation, Damage, Electrodes, Maintenance, Nanopores
Proceedings Papers

Separation Analysis of Breast Cancer Progression Lines Using Contactless Dielectrophoresis

Andrea D. Rojas, Eva M. Schmelz, Rafael V. Davalos
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 1069-1070, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53987
https://doi.org/10.1115/SBC2011-53987
View Paper titled, Separation Analysis of Breast Cancer Progression Lines Using Contactless Dielectrophoresis
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Topics: Cancer, Dielectrophoresis, Separation (Technology), Flow (Dynamics), Lasers, Microparticles
Proceedings Papers

Mixing Enhancement in Microfluidic Devices Using Contactless Dielectrophoresis (cDEP)

Alireza Salmanzadeh, Hadi Shafiee, Mark A. Stremler, Rafael V. Davalos
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 1071-1072, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-54008
https://doi.org/10.1115/SBC2011-54008
View Paper titled, Mixing Enhancement in Microfluidic Devices Using Contactless Dielectrophoresis (cDEP)
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Topics: Bubbles, Contamination, Delamination, Dielectrophoresis, Diffusion (Physics), Electric fields, Electrodes, Electrokinetics, Electrolysis, Microfluidics
Proceedings Papers

A Method to Delineate Irreversible Electroporation From Thermal Damage Validated Ex Vivo With Real-Time Temperature

Paulo A. Garcia, John H. Rossmeisl, Jr., Thomas L. Ellis, Rafael V. Davalos
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 577-578, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53883
https://doi.org/10.1115/SBC2011-53883
View Paper titled, A Method to Delineate Irreversible Electroporation From Thermal Damage Validated Ex Vivo With Real-Time Temperature
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Topics: Damage, Electroporation, Temperature, Biological tissues, Ablation (Vaporization technology), Brain, Cell membranes, Electric fields, Electrodes, Membranes
Proceedings Papers

Enrichment of Cancer Cells Using a High Throughput Contactless Dielectrophoretic (CDEP) Microfluidic Device

Alireza Salmanzadeh, Hadi Shafiee, Mike B. Sano, Mark A. Stremler, Rafael V. Davalos
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 47-48, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-54011
https://doi.org/10.1115/SBC2011-54011
View Paper titled, Enrichment of Cancer Cells Using a High Throughput Contactless Dielectrophoretic (CDEP) Microfluidic Device
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Topics: Cancer, Microfluidics, Blood, Tumors, Electrical properties, Particulate matter, Biomedicine, Dielectrophoresis, Electric fields, Electrical conductivity